Result files of the KP6 detection protocole (the output of each step is usually the input of next one):

1) Reference PDB templates for TMalign validation: 2 proteins

2) Structural alignment of 1KP6 Foldseek hits with TM-score>0.5: 135 proteins

3) Hmmer hits in Fungi secretomes (length<180, 10 iterations, E-value<1, Overlap>=75%): 433 proteins

4) Structural alignment of ZtKP6 Foldseek hits with TM-score>0.5: 116 proteins

5) Hmmer hits in Fungi secretomes (length<180, 10 iterations, E-value<1, Overlap>=75%): 630 proteins

6) Representatives of AFDB clusters similar to those detected by Foldseek (E-val<0.001, sequence<180aa and more than 50% fungal cluster members: 84 proteins

7) Representatives of AFDB clusters covering all hits: 158 proteins

8) AFDB cluster representatives shorter than 180 aa and not transmembrane: 146 proteins

9) TMalign structural alignment of AFDB representatives versus 4gvbA template: 147 proteins

10) AFDB representatives with TM-score>=0.5 versus 4gvbA template: 79 proteins

11) TMalign structural alignment of AFDB representatives versus 6qpkA template: 147 proteins

12) AFDB representatives with TM-score>=0.5 versus 6qpkA template: 66 proteins

13) Accession numbers of the AFDB representatives validated by any template: 81 proteins

14) Corresponding secreted AFDB50 cluster representatives (sharing less than 50% seq identity): 336 proteins

15) TM-scores of detected cluster representatives vs 4gvbA (columns with >50% gaps removed): 81 proteins

16) AFDB50 representatives alignment with taxonomic information (columns with >50% gaps removed): 81 proteins

17) Phylogenetic tree of ADFB50 representatives: 81 proteins

18) All validated AFDB cluster members: 2557 proteins

19) Taxonomic distribution of all detected KP6 folds: 1506 proteins

20) Most frequent Uniprot annotations: 1506 proteins

21) TMalign alignment of Hmmer hits in Zymoseptoria tritici (vs 6qpkA): 8 proteins

22) TM-scores of all Zymoseptoria tritici proteins in final set (vs 6qpkA): 14 proteins

23) Same alignment with 2D structure information added: 14 proteins

24) FastME tree of all Zymoseptoria tritici proteins in final set (vs 6qpkA): 14 proteins

25) Clustering at 30%id and 60% overlap of KP6 detected by FHAT or Krasileva or Raffaele: 478 proteins

26) Comparison between protocoles FHAT - Krasileva - Raffaele: 478 proteins

27) Structural alignment by TMalign of selected proteins vs 6qpkA (prefix OK=>detected, No=>not detected): 23 proteins

28) FastME tree derived from structural aligment of selected proteins (OK=>detected, No=>not detected): 23 proteins

29) Representatives from representatives 1D+2D clustering (at 40%id max): 17 proteins

30) Representatives from ZYMTR hits 1D clustering (at 40%id max): 5 proteins

31) Representatives from selected proteins clustering (at 30%id max): 10 proteins

32) FHAT + ZYMTR + MHL representatives + A0A0F4GFX5 + KP6_like_v6_MHL.slx in FASTA format: 45 proteins

33) FHAT + ZYMTR + MHL representatives + A0A0F4GFX5 + KP6_like_v6_MHL.slx in PDB format (TGZ archive): 45 proteins

34) Uniprot annotations from FHAT+ZYMTR+MHL representatives: 40 proteins

35) FHAT+ZYMTR+MHL representatives structural alignment from TMalign vs 6qpkA (without columns with more than 50% gaps): 46 proteins

36) FHAT+ZYMTR+MHL FastME tree derived from TMalign alignment without 50%gap columns: 46 proteins

37) FHAT+ZYMTR+MHL FastME tree derived from TMalign alignment without 50%gap columns with Pfam suffixes: 46 proteins

38) Comparison of FHAT+ZYMTR+MHL trees derived from TM-scores matrix (left) and TMalign structural alignment (right): 46 proteins