Sorted listing of the 20 most frequent annotations by category (+ some corresponding Uniprot entries) Total number of analyzed Uniprot entries: 40 P16948 A0A1F8AGI7 A0A1P8YXM5 A0A2H1G421 M1W1H7 Descriptions Num Lines Uniprot entries (up to 5) 5 Cyanovirin-N domain-containing protein E5A720 A0A2H1G421 A0A2H1H0K4 A0A2G5HLK5 M1W1H7 4 Extracellular membrane protein CFEM domain-containing protein A0A2H1GHJ3 A0A1E1M101 A0A1F8AGI7 A0A1X2ISA0 1 Biotrophy-associated secreted protein 4 G5EI20 1 KP6 killer toxin subunit alpha; P16948 1 Candidate secreted effector protein A0A8H3U9R5 1 KP6 killer toxin subunit beta; P16948 1 KP6 killer toxin; P16948 1 Secreted protein A0A4R8TM13 1 Inhibitor I9 domain-containing protein A0A1E4RY46 1 Thiamine-binding protein domain-containing protein Q2H9X5 Species Num Lines Uniprot entries (up to 5) 7 Zymoseptoria tritici ST99CH_1E4. A0A2H1GHJ3 A0A2H1G421 A0A2H1H0K4 A0A2H1FMK1 A0A2H1GZA7 3 Zymoseptoria brevis. A0A0F4GGQ1 A0A0F4GMG5 A0A0F4GFX5 3 Passalora fulva Tomato leaf mold Cladosporium fulvum . A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 2 Fusarium oxysporum Fusarium vascular wilt . A0A089H101 A0A7G5WH58 1 Colletotrichum sidae. A0A4R8TM13 1 Blackleg fungus Phoma lingam . E5A720 1 Stereum hirsutum strain FP-91666 White-rot fungus . R7RXA0 1 Emergomyces pasteurianus Ep9510. A0A1J9QSS6 1 Magnaporthe oryzae strain 70-15 / ATCC MYA-4617 / FGSC 8958 Rice blast G5EI20 1 corn leaf blight fungus Bipolaris maydis . M2SJA7 1 Ustilago maydis P6 virus UmV6 UmV-P6 . P16948 1 Chaetomium globosum strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / Q2H9X5 1 fungus Pyricularia oryzae . G5EI20 1 Fusarium oxysporum strain Fo5176 Fusarium vascular wilt . F9FAC2 1 Candida glabrata Yeast Torulopsis glabrata . A0A0W0C984 1 Cyberlindnera jadinii strain ATCC 18201 / CBS 1600 / BCRC 20928 / JCM 3617 A0A1E4RY46 1 / NBRC 0987 / NRRL Y-1542 Torula yeast Candida utilis . A0A1E4RY46 1 Rhynchosporium secalis Barley scald fungus . A0A1E1M101 1 Claviceps purpurea strain 20.1 Ergot fungus Sphacelia segetum . M1W1H7 1 Venturia inaequalis Apple scab fungus . A0A8H3U9R5 Taxonomies Num Lines Uniprot entries (up to 5) 20 Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes; A0A2H1GHJ3 A0A1P8YXM5 A0A6S6WCA4 A0A1P8YXM1 A0A2H1FMJ4 12 Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes; F9FAC2 K7N7G0 A0A4R8TM13 G5EI20 A0A135SXI2 10 Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria. A0A2H1GHJ3 A0A0F4GMG5 A0A2H1H0K4 A0A2H1GZA7 A0A2H1FMJ4 4 Fusarium oxysporum species complex. F9FAC2 X0MJF4 A0A089H101 A0A7G5WH58 4 Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium; F9FAC2 X0MJF4 A0A089H101 A0A7G5WH58 4 Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum; K7N7G0 A0A4R8TM13 A0A135SXI2 A0A4V3HRP1 3 Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Fulvia. A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 2 Colletotrichum orbiculare species complex. A0A4R8TM13 A0A4V3HRP1 2 Pleosporomycetidae; Pleosporales; Pleosporineae; Leptosphaeriaceae; E5A720 A4F4L2 2 Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; A0A1F8AGI7 A0A1J9QSS6 2 Pyrenophora. A0A6S6WCA4 A0A317AKI4 2 Plenodomus; Plenodomus lingam/Leptosphaeria maculans species complex. E5A720 A4F4L2 2 Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; A0A6S6WCA4 A0A317AKI4 2 Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; A0A0W0C984 A0A1E4RY46 2 Sordariomycetidae; Magnaporthales; Pyriculariaceae; Pyricularia. L7IRH8 G5EI20 1 Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; A0A1E1M101 1 Eurotiomycetidae; Onygenales; Ajellomycetaceae; Emergomyces. A0A1J9QSS6 1 Pleosporomycetidae; Pleosporales; Pleosporineae; Pleosporaceae; Bipolaris. M2SJA7 1 Colletotrichum acutatum species complex. A0A135SXI2 1 Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes; R7RXA0 Publication titles Num Lines Uniprot entries (up to 5) 3 "RNA-seq based gene annotation and comparative genomics of four A0A0F4GGQ1 A0A0F4GMG5 A0A0F4GFX5 3 "Novel effectors identified in the apoplast of Cladosporium fulvum-infected A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 3 "A chromosome-scale genome assembly of the tomato pathogen Cladosporium A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 3 Zymoseptoria species reveal species-specific pathogenicity related genes A0A0F4GGQ1 A0A0F4GMG5 A0A0F4GFX5 3 fulvum reveals a compartmentalized genome architecture and the presence of A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 3 tomato."; A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 3 and transposable element activity."; A0A0F4GGQ1 A0A0F4GMG5 A0A0F4GFX5 3 a dispensable chromosome."; A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 1 "The biotrophy-associated secreted protein 4 BAS4 participates in the G5EI20 1 "Comparative analysis of the genomes of two field isolates of the rice L7IRH8 1 "Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the M1W1H7 1 "Heterochromatin-like regions as ecological niches for avirulence genes in A4F4L2 1 "Mutants of Ustilago maydis defective in production of one of two P16948 1 "Translocation of Magnaporthe oryzae effectors into rice cells and their G5EI20 1 "Sequential delivery of host-induced virulence effectors by appressoria and K7N7G0 1 "A global pangenome for the wheat fungal pathogen Pyrenophora tritici- A0A317AKI4 1 "Interaction transcriptome analysis identifies Magnaporthe oryzae BAS1-4 as G5EI20 1 "The Paleozoic origin of enzymatic lignin decomposition reconstructed from R7RXA0 1 "Genomic Plasticity Mediated by Transposable Elements in the Plant K7N7G0 1 "The cercosporin biosynthetic gene cluster was horizontally transferred to A0A2G5HLK5 Pubmed records Num Lines Uniprot entries (up to 5) 3 PubMed=35471194; A0A1P8YXM5 A0A1P8YXM1 A0A1P8YXQ5 1 PubMed=27664179; A0A1F8AGI7 1 PubMed=31049006; DOI=10.1016/j.sjbs.2019.01.003; G5EI20 1 PubMed=21942452; DOI=10.1094/mpmi-08-11-0212; F9FAC2 1 PubMed=2181272; DOI=10.1128/mcb.10.4.1373-1381.1990; P16948 1 PubMed=23468653; DOI=10.1371/journal.pgen.1003323; M1W1H7 1 PubMed=20435900; DOI=10.1105/tpc.109.069666; G5EI20 1 PubMed=17427816; DOI=10.1094/MPMI-20-4-0459; A4F4L2 1 PubMed=15846337; DOI=10.1038/nature03449; G5EI20 1 PubMed=29685100; DOI=10.1186/s12864-018-4680-3; A0A317AKI4 1 PubMed=19357089; DOI=10.1105/tpc.107.055228; G5EI20 1 PubMed=23357949; DOI=10.1371/journal.pgen.1003233; M2SJA7 1 PubMed=31028389; DOI=.1093/gbe/evz087; K7N7G0 1 PubMed=21326234; DOI=10.1038/ncomms1189; E5A720 1 PubMed=22876203; DOI=10.1371/journal.pgen.1002869; L7IRH8 1 PubMed=25720678; DOI=10.1128/genomeA.00021-15; Q2H9X5 1 PubMed=10400668; DOI=10.1074/jbc.274.29.20425; P16948 1 PubMed=27535936; DOI=10.1073/pnas.1603941113; A0A1E4RY46 1 PubMed=8479428; DOI=10.1007/bf00279552; P16948 1 PubMed=22745431; DOI=10.1126/science.1221748; R7RXA0 Comments Num Lines Uniprot entries (up to 5) 1 independently, as monomers. P16948 1 compatible interaction PubMed:19357089 . G5EI20 1 -!- MISCELLANEOUS: The KP6 toxin polypeptides interact with the cell P16948 1 -!- SUBCELLULAR LOCATION: Secreted G5EI20 1 -!- INDUCTION: Expression is highly up-regulated in invasive hyphae. G5EI20 1 related species. The KP6 alpha subunit is known to recognize some P16948 1 PubMed:31049006 . Elicits rice basic defense responses during the G5EI20 1 linked. P16948 1 ECO:0000269|PubMed:31049006}. G5EI20 1 biotrophic to the necrotrophic phase of Magnaporthe oryzae G5EI20 1 early stage of interaction and promotes cell death in the late stage of G5EI20 1 hyphal membrane EIHM matrix. G5EI20 1 cellular receptors before interaction of the complex with KP6 beta, P16948 1 -!- FUNCTION: Secreted effector involved in biotrophic colonization of G5EI20 1 -!- FUNCTION: This protein is lethal to sensitive cells of the same or P16948 1 -!- SIMILARITY: Belongs to the UPF0045 family. Q2H9X5 1 precipitating cell death. P16948 1 ECO:0000269|PubMed:20435900}. Note=Localizes to the extra-invasive G5EI20 1 ECO:0000269|PubMed:20435900}. G5EI20 1 -!- SUBCELLULAR LOCATION: Secreted. P16948 All databases Num Lines Uniprot entries (up to 5) 5 Pfam; PF19373; DUF5948; 1. A0A1P8YXM5 A0A1E1M101 R7RXA0 A0A1X2ISA0 A0A1P8YXQ5 5 InterPro; IPR045992; DUF5948. A0A1P8YXM5 A0A1E1M101 R7RXA0 A0A1X2ISA0 A0A1P8YXQ5 2 SUPFAM; SSF54897; Protease propeptides/inhibitors; 1. A0A0W0C984 A0A1E4RY46 2 OrthoDB; 2459452at2759; -. A0A1P8YXM5 A0A1P8YXM1 2 GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. P16948 G5EI20 2 InterPro; IPR037045; S8pro/Inhibitor_I9_sf. A0A0W0C984 A0A1E4RY46 2 Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1. A0A0W0C984 A0A1E4RY46 1 EMBL; HE651169; CCF70888.1; -; mRNA. K7N7G0 1 CDD; cd22805; KP6_beta; 1. P16948 1 AlphaFoldDB; A0A1P8YXQ5; -. A0A1P8YXQ5 1 InterPro; IPR006121; HMA_dom. A0A1J9QSS6 1 AlphaFoldDB; A0A0W0C984; -. A0A0W0C984 1 GeneID; 4389002; -. Q2H9X5 1 AlphaFoldDB; A0A1F8AGI7; -. A0A1F8AGI7 1 PHI-base; PHI:1131; -. A4F4L2 1 AlphaFoldDB; A0A317AKI4; -. A0A317AKI4 1 PDB; 4GVB; X-ray; 1.80 A; A=28-107, B=139-219. P16948 1 EMBL; LGRN01000014; OJD19255.1; -; Genomic_DNA. A0A1J9QSS6 1 NCBIfam; TIGR00106; MTH1187 family thiamine-binding protein; 1. Q2H9X5 1 RefSeq; XP_020069252.1; XM_020216587.1. A0A1E4RY46 InterPro families Num Lines Uniprot entries (up to 5) 5 InterPro; IPR045992; DUF5948. A0A1P8YXM5 A0A1E1M101 R7RXA0 A0A1X2ISA0 A0A1P8YXQ5 2 InterPro; IPR037045; S8pro/Inhibitor_I9_sf. A0A0W0C984 A0A1E4RY46 1 InterPro; IPR006121; HMA_dom. A0A1J9QSS6 1 InterPro; IPR002767; Thiamine_BP. Q2H9X5 1 InterPro; IPR029756; MTH1187/YkoF-like. Q2H9X5 1 InterPro; IPR036163; HMA_dom_sf. A0A1J9QSS6 Pfam domains Num Lines Uniprot entries (up to 5) 5 Pfam; PF19373; DUF5948; 1. A0A1P8YXM5 A0A1E1M101 R7RXA0 A0A1X2ISA0 A0A1P8YXQ5 1 Pfam; PF01910; Thiamine_BP; 1. Q2H9X5 Other families Num Lines Uniprot entries (up to 5) 2 SUPFAM; SSF54897; Protease propeptides/inhibitors; 1. A0A0W0C984 A0A1E4RY46 2 Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1. A0A0W0C984 A0A1E4RY46 1 CDD; cd22805; KP6_beta; 1. P16948 1 SUPFAM; SSF55008; HMA, heavy metal-associated domain; 1. A0A1J9QSS6 1 SUPFAM; SSF55056; Killer toxin KP6 alpha-subunit; 1. P16948 1 Gene3D; 3.30.70.440; Killer toxin KP6 alpha-subunit; 2. P16948 1 CDD; cd22804; KP6_alpha; 1. P16948 1 Gene3D; 3.30.70.100; -; 1. A0A1J9QSS6 1 Gene3D; 3.30.70.930; -; 1. Q2H9X5 1 SUPFAM; SSF89957; MTH1187/YkoF-like; 1. Q2H9X5 1 CDD; cd00371; HMA; 1. A0A1J9QSS6 Phylogeny databases Num Lines Uniprot entries (up to 5) 2 OrthoDB; 2459452at2759; -. A0A1P8YXM5 A0A1P8YXM1 1 PhylomeDB; A0A0W0C984; -. A0A0W0C984 1 HOGENOM; CLU_2278030_0_0_1; -. G5EI20 1 OrthoDB; 1107952at2759; -. A0A1J9QSS6 1 OrthoDB; 1928370at2759; -. A0A1E4RY46 1 eggNOG; ENOG502SYWT; Eukaryota. E5A720 1 OrthoDB; 2174702at2759; -. A0A135SXI2 1 OMA; WATEKAC; -. A0A1P8YXM1 1 OMA; MRASFTI; -. R7RXA0 1 OrthoDB; 2645543at2759; -. M1W1H7 1 OMA; AYGTNIE; -. Q2H9X5 1 OrthoDB; 1573219at2759; -. R7RXA0 1 OrthoDB; 1437941at2759; -. A0A1X2ISA0 1 OrthoDB; 2561845at2759; -. A0A2G5HLK5 1 OrthoDB; 2431515at2759; -. E5A720 1 HOGENOM; CLU_2249871_0_0_1; -. M2SJA7 1 HOGENOM; CLU_137479_0_0_1; -. Q2H9X5 1 PANTHER; PTHR46365; COPPER TRANSPORT PROTEIN ATOX1; 1. A0A1J9QSS6 1 OrthoDB; 2785369at2759; -. Q2H9X5 1 PANTHER; PTHR33777; UPF0045 PROTEIN ECM15; 1. Q2H9X5 Structures Num Lines Uniprot entries (up to 5) 1 PDBsum; 1KP6; -. P16948 1 PDB; 6QPK; X-ray; 1.36 A; A/B=20-96. A0A2H1G421 1 PDBsum; 6QPK; -. A0A2H1G421 1 PDB; 4GVB; X-ray; 1.80 A; A=28-107, B=139-219. P16948 1 PDBsum; 4GVB; -. P16948 1 PDB; 1KP6; X-ray; 1.80 A; A=28-106. P16948 GO classes Num Lines Uniprot entries (up to 5) 2 GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. P16948 G5EI20 1 GO; GO:0042144; P:vacuole fusion, non-autophagic; IEA:EnsemblFungi. A0A0W0C984 1 GO; GO:0046872; F:metal ion binding; IEA:InterPro. A0A1J9QSS6 1 GO; GO:0004866; F:endopeptidase inhibitor activity; IEA:EnsemblFungi. A0A0W0C984 1 GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW. P16948 Keywords Num Lines Uniprot entries (up to 5) 30 Signal A0A2H1GHJ3 A0A1E4RY46 K7N7G0 A0A1P8YXM1 A4F4L2 1 Direct protein sequencing; Disulfide bond; Glycoprotein; Secreted; Signal; P16948 1 3D-structure A0A2H1G421 1 Toxin. P16948 1 Copper A0A1J9QSS6 1 3D-structure; Cleavage on pair of basic residues; P16948 Features Num Lines Uniprot entries (up to 5) 5 /note="Cyanovirin-N domain-containing protein" E5A720 A0A2H1G421 A0A2H1H0K4 A0A2G5HLK5 M1W1H7 3 /note="Extracellular membrane protein CFEM domain- A0A2H1GHJ3 A0A1E1M101 A0A1F8AGI7 2 /note="Basic and acidic residues" Q2H9X5 P16948 2 /note="Disordered" Q2H9X5 P16948 1 /note="Biotrophy-associated secreted protein 4" G5EI20 1 /note="KP6 killer toxin subunit alpha" P16948 1 /note="C -> R in strain: NK3 " P16948 1 /note="Thiamine-binding protein" Q2H9X5 1 /note="KP6 killer toxin subunit beta" P16948 1 /note="Inhibitor I9 domain-containing protein" A0A1E4RY46 1 /note="Candidate secreted effector protein" A0A8H3U9R5 1 /note="Secreted protein" A0A4R8TM13 1 /note="T -> P in strain: NK13 " P16948 1 /note="N-linked GlcNAc... asparagine" G5EI20 1 /note="K -> R in strain: NK13 " P16948 1 /note="N-linked GlcNAc... asparagine; by host" P16948